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2001

選考理由書
生命系応用分野

選考理由
業績とその創造性
1. 高速自動キャピラリ型DNAシーケンサの開発
2. 全ゲノムショットガン戦略の確立
3. ゲノム研究の社会に与えた影響
4. 参考文献
図1
図2
図3
図4

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▼情報・電子系応用分野 ▼生命系応用分野 ▼環境系応用分野
業績とその創造性
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4. 参考文献

(1) Maxam, A.M., and Gilbert, W., "A new method for sequencing DNA," Proc .Natl. Acad. Sci. U.S.A. 74, 560-564 (1977).
(2) Sanger, F., Nicklen, S., and Coulson, A.R., "DNA sequencing with chain-terminating inhibitors," Proc. Acad. Natl. Sci. U.S.A. 74, 5463-5467 (1977).
(3) Smith, L.M., Sanders, J.Z., Kaiser, R.J., Hughes, P., Dodd, C., Connell, C.R., Heiner, C., Kent, S.B.H., and Hood, L.E., "Fluorescence detection in automated DNA sequence analysis," Nature 321, 674-679 (1986).
(4) Ansorge, W., Soroat, B.S., Stegemann, J., and Schwager, C., "A non-radioactive automated method for DNA sequence determination," J. Biochem. Biophys. Methods 13, 315-323 (1986).
(5) Prober, J.M., Trainer, G.L., Dam, R.J., Hobbs, F.W., Robertson, C.W., Zagursky, R.J., Cocuzza, A.J., Jensen, M.A., Baumeister, K., "A system for rapid DNA sequencing with fluorescent chain-terminating dideoxynucleotides," Science 238, 336-341 (1987).
(6) Smith, L.M., Hood, L.E., Hunkapiller, M.W., and Hunkapiller, T.J., "Automated DNA sequencing technique," USP 5,171,534 (1992).
(7) Drossman, H., Luckey, J.A., Kostichka, A.J., D'Cunha, J., and Smith, L.M., "High-speed separation of DNA sequencing reactions by capillary electrophoresis," Anal. Chem. 62, 900-903 (1990).
(8) Guttman, A., Cohen, A.S., Heiger, D.N., Karger, B.L., "Analytical and micropreparative ultrahigh resolution of oligonucleotides by polyacrylamide gel high-performance capillary electrophoresis," Anal. Chem. 62, 137-141 (1990).
(9) Swerdlow, H., and Gestaland, R., "Capillary gel elelctrophoresis for rapid, high resolution DNA sequencing," Nuc. Acids Res. 18, 1415-1419 (1990).
(10) Huang, X., Quesada, M.A., and Mathies, R.A., "Capillary Array Electrophoresis Using Laser-induced Confocal Fluorescence Detection," Anal. Chem. 64, 967-972(1992).
(11) Kambara, H., and Takahashi, S., "Multiple-sheath flow capillary array DNA analyzer," Nature 361, 565-566 (1993).
(12) Dovichi, N.J., and Zhang, J.Z., "Multiple capillary biochemical analyzer," USP 5,439,578 (1995).
(13) Adams,M.D.,et al.,"Complementary DNA Sequencing:Sequence Tag's and the Human Genome Project," Science 252,1451-1456(1991).
(14) Fleischmann, R.D., et al., "Whole-genome random sequencing and assembly of Haemophilus influenzae Rd,"Science 269, 496-512 (1995).
(15) Davies, K., in "Cracking the genome," Free Press, New York (2001).
(16) Venter, J.C., Adams, M.D., Sutton, G.G., Kerlavage, A.R., Smith, H.O., and Hunkapiller, M., "Shotgun sequencing of the human genome," Science280, 1540-1542, (1998).
(17) Venter, J.C., et al., "The sequence of the human genome," Science 291, 1304-1351, (2001).
(18) Myers, E.W., in "A Whole-Genome Assembly of Drosophila," Science 287, 2196-2204, (2000).Adams,M.D.,et al.,"The Genome Sequence of Drosophila Melanogaster." Science 280,2185-2195(2000).
(19) International Human Genome Sequencing Consortium, "Initial sequencing and analysis of the human genome," Nature 409, 860-921 (2001).
(20) "Convergence: the Biotechnology Industry Report," Ernst & Young LLP, Millennium edition, p16, (2000).
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